TECHNOLOGICAL BREAKTHROUGH OF HISTORY/ ANTIBIOTICS/S.B
WHO?
The first antibiotic, penicillin, was discovered by Alexander Fleming in 1928.
WHAT?
Antiobiotics are powerful medicines that fight bacterial infections. Used properly, antibiotics can save lives. They either kill bacteria or keep them from reproducing. Your body's natural defenses can usually take it from there.
WHEN?
Antibiotics were discovered by Alexander Fleming in 1928 but the first commercially available antibacterial was Prontosil, a sulfonamide developed by the German biochemist Gerhard Domagk in the 1930s. Between 1940 and 1962, most of the antibiotic classes we use as medicines today were discovered and introduced to the market.
WHERE?
It was discovered at St. Mary's Hospital in London.
WHY?
Fleming described the colony as a “fluffy white mass which rapidly increases in size and after a few days sporulates” and changes color from dark green to black to bright yellow.
Even in the early experimentation stages, penicillin had no effect against gram-negative organisms but was effective against gram-positive bacteria.
HOW?
It was discovered by a accident but the process was this way: An article published by Fleming in the British Journal of Experimental Pathology in 1929 reads, “The staphylococcus colonies became transparent and were obviously undergoing lysis … the broth in which the mold had been grown at room temperature for one to two weeks had acquired marked inhibitory, bactericidal and bacteriolytic properties to many of the more common pathogenic bacteria.”
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